Improved Large-Bore Vascular Closure Device

A Vascular Closure Device that achieves optimal closure of the vascular access site through a new mechanism of delivery sheath with side window and peel-away design together with a stent graft with improved features


The rapidly growing volume of minimally invasive, totally percutaneous large bore interventions includes transcatheter aortic valve replacement (TAVR), endovascular aortic aneurysm repair (EVAR), thoracic endovascular aortic repair (TEVAR) and mechanical circulatory support (MCS).

These procedures require the creation of a 10- 25 Fr (3.3 – 8.3 mm ) vascular access site in the femoral artery which is sealed following completion of the procedure by a vascular closure device (VCD).

Current suture and plug based VCD have suboptimal design and result in device failure in 5% and significant bleeding in > 10% of cases.

VCD failure increases length of hospital stay, procedural cost and mortality.


Dr. Ronen Jaffe, Carmel Medical Center

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Avital Pritz, Director of Medical Devices and Digital Health

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A novel VCD designed to achieve optimal closure of the vascular access site by suggesting a new mechanism of delivery sheath with a “side window” and peel away design, as well as a stent graft with improved features

The global Vascular Closure Devices market size was valued at USD 923.04 million in 2021 and is expected to grow at a CAGR of 7.0% reaching USD $1.3 billion by 2027.

The growth is attributed to the large number of approvals for VCDs, high prevalence of cardiovascular diseases, increasing prevalence of obesity, a growing geriatric population, increasing focus of market players on large-bore VCDs, a favorable reimbursement scenario for interventional radiology procedures, and the rising focus on effective blood loss management in patients during surgery.

The concept has been developed.

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